Recombinant Mouse Elob Protein, Myc/DDK-tagged

• Cat.No.: Elob-2802M
• Product Overview: Purified recombinant protein of mouse full-length elongin B (Elob), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.
• Molecular Mass: 13.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Elob elongin B [ Mus musculus (house mouse) ]
• Official Symbol: Elob
• Synonyms: Elob; elongin B; Tceb2; 0610040H15Rik; elongin-B; 18 kDa, elongin B; RNA polymerase II transcription factor SIII subunit B; SIII p18; elongin 18 kDa subunit; transcription elongation factor B (SIII), polypeptide 2 (18 kDa, elongin B); transcription elongation factor B polypeptide 2
• Gene ID: 67673
• mRNA Refseq: NM_026305
• Protein Refseq: NP_080581
• UniProt ID: P62869