Recombinant Mouse Ecsit Protein, Myc/DDK-tagged

• Cat.No.: Ecsit-2721M
• Product Overview: Purified recombinant protein of mouse full-length ECSIT signalling integrator (Ecsit), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 50.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ecsit ECSIT signalling integrator [ Mus musculus (house mouse) ]
• Official Symbol: Ecsit
• Synonyms: ECSIT; ECSIT homolog (Drosophila); evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; signaling intermediate in Toll pathway-evolutionarily conserved; Sitpec
• Gene ID: 26940
• mRNA Refseq: NM_012029
• Protein Refseq: NP_036159
• UniProt ID: Q9QZH6