Recombinant Mouse Dlg2 Protein, Myc/DDK-tagged

• Cat.No.: Dlg2-2575M
• Product Overview: Purified recombinant protein of mouse full-length discs large MAGUK scaffold protein 2 (Dlg2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
• Molecular Mass: 94.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dlg2 discs large MAGUK scaffold protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Dlg2
• Synonyms: DLG2; discs, large homolog 2 (Drosophila); disks large homolog 2; chapsyn-110; postsynaptic density protein PSD-93; channel-associated protein of synapse-110; Dlgh2; PSD93; Gm1197; A330103J02Rik; B230218P12Rik; B330007M19Rik
• Gene ID: 23859
• mRNA Refseq: NM_011807
• Protein Refseq: NP_035937
• UniProt ID: Q91XM9