Recombinant Mouse Dis3l Protein, Myc/DDK-tagged

• Cat.No.: Dis3l-2569M
• Product Overview: Purified recombinant protein of mouse full-length DIS3 like exosome 3'-5' exoribonuclease (Dis3l), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 110.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dis3l DIS3 like exosome 3'-5' exoribonuclease [ Mus musculus (house mouse) ]
• Official Symbol: Dis3l
• Synonyms: DIS3L; DIS3 mitotic control homolog (S. cerevisiae)-like; DIS3-like exonuclease 1; AV340375
• Gene ID: 213550
• mRNA Refseq: NM_001177784
• Protein Refseq: NP_001171255
• UniProt ID: Q8C0S1