Recombinant Mouse Ddi1 Protein, Myc/DDK-tagged

• Cat.No.: Ddi1-2492M
• Product Overview: Purified recombinant protein of mouse full-length DNA-damage inducible 1 (Ddi1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Probable aspartic protease. Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 45.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ddi1 DNA-damage inducible 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ddi1
• Synonyms: DDI1; DDI1, DNA-damage inducible 1, homolog 1 (S. cerevisiae); protein DDI1 homolog 1; 1700011N24Rik
• Gene ID: 71829
• mRNA Refseq: NM_027942
• Protein Refseq: NP_082218
• UniProt ID: Q9DAF3