Recombinant Mouse Crhr1 Protein, His-tagged

• Cat.No.: Crhr1-842M
• Product Overview: Recombinant Mouse Crhr1 Protein (Ser24-Cys149) with His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Ser24-Cys149
• Description: The protein encoded by this gene is a G-protein coupled receptor that binds corticotropin-releasing factor (CRH) and urocortin (UCN) with high affinity. The encoded protein upregulates adenylate cyclase activity and intracellular cAMP levels. This protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response, and obesity. Several transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 17.8 kDa; Accurate Molecular Mass: 16 kDa
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Crhr1 corticotropin releasing hormone receptor 1 [ Mus musculus (house mouse) ]
• Official Symbol: Crhr1
• Synonyms: CRHR1; corticotropin releasing hormone receptor 1; corticotropin-releasing factor receptor 1; CRF-R1; CRFR-1; CRH-R1; CRF-R-1; CRH-R-1; CRF-R1alpha; CRF 1 receptor; corticotropin-releasing hormone receptor 1; Crhr; CRFR1; MGC124237; MGC124240
• Gene ID: 12921
• mRNA Refseq: NM_007762
• Protein Refseq: NP_031788
• UniProt ID: Q3ZAT0