Recombinant Mouse Cmtr1 Protein, Myc/DDK-tagged

• Cat.No.: Cmtr1-2213M
• Product Overview: Purified recombinant protein of mouse full-length cap methyltransferase 1 (Cmtr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m7GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
• Molecular Mass: 95.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cmtr1 cap methyltransferase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Cmtr1
• Synonyms: Cmtr1; cap methyltransferase 1; MTr1; Ftsjd; Ftsjd2; AI451264; 1300018I05Rik; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; FtsJ methyltransferase domain-containing protein 2; S-adenosyl-L-methionine-dependent methyltransferase FTSJD2; cap1 2'O-ribose methyltransferase 1; EC 2.1.1.57
• Gene ID: 74157
• mRNA Refseq: NM_028791
• Protein Refseq: NP_083067
• UniProt ID: Q9DBC3