Recombinant Mouse Cfd Protein, MYC/DDK-tagged

• Cat.No.: Cfd-546M
• Product Overview: Purified recombinant protein of full-length mouse complement factor D (adipsin) (Cfd), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a serine protease that plays an important role in the alternative pathway of complement activation for pathogen recognition and elimination. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme that in turn cleaves factor B in the complement pathway. This gene is expressed in adipocytes and the mature enzyme is secreted into the bloodstream. Mice lacking the encoded product cannot initiate alternative pathway of complement activation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 28.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cfd complement factor D (adipsin) [ Mus musculus (house mouse) ]
• Official Symbol: Cfd
• Synonyms: Cfd; complement factor D (adipsin); DF; Adn; complement factor D; 28 kDa adipocyte protein; C3 convertase activator; D component (adipsin) of complement; properdin factor D; EC 3.4.21.46
• Gene ID: 11537
• mRNA Refseq: NM_013459
• Protein Refseq: NP_038487
• UniProt ID: P03953