Recombinant Mouse Cep19 Protein, Myc/DDK-tagged

• Cat.No.: Cep19-2112M
• Product Overview: Purified recombinant protein of mouse full-length centrosomal protein 19 (Cep19), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 19.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cep19 centrosomal protein 19 [ Mus musculus (house mouse) ]
• Official Symbol: Cep19
• Synonyms: Cep19; centrosomal protein 19; AI428934; AL022620; 1500031L02Rik; centrosomal protein of 19 kDa
• Gene ID: 66994
• mRNA Refseq: NM_025892
• Protein Refseq: NP_080168
• UniProt ID: Q9CQA8