Recombinant Mouse CD48 Antigen, His-tagged

• Cat.No.: Cd48-3293M
• Product Overview: Recombinant Mouse Cd27 (extracellular domain, Met 1 - Arg 182), fused with a His-tag at C-terminus, was expressed inHuman Cells.

Specification

• Cat. No.: Cd27-3273M
• Description: Mouse CD27, also known as TNFRSF7, is a member of the tumor necrosis factor receptor (TNFR) superfamily characterized by the presence of a Cys-knot motif in the extracellular region, which occurs three times in CD27. CD27 is a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, and has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis. CD27 has been defined as a T and B cell co-stimulatory molecule, and its activity is governed by the transient availability of its TNF-like ligand CD70 on lymphocytes and dendritic cells. In man and mouse, CD27 is restricted to lymphoid cells and present on the great majority of naive CD4+ and CD8 + T cells.
• Source: Human Cells.
• Molecular Mass: The recombinant mouse CD27 consists of 173 amino acids after removal of the signal peptide and has a predicted molecular mass of 19.6 kDa. In SDS-PAGE under reducing conditions, rmCD27 migrates as an approximately 35 kDa band due to glycosylation.
• Predicted N Terminal: Thr 21.
• Purity: > 96 % as determined by SDS-PAGE.
• Formulation: Lyophilized from sterile PBS, pH 7.4.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃.
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: Cd27 CD27 antigen [ Mus musculus ]
• Synonyms: Cd27; CD27 antigen; S152; Tp55; Tnfrsf7; CD antigen 27; CD27L receptor; OTTMUSP00000029268; OTTMUSP00000029269; OTTMUSP00000029270; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
• Gene ID: 21940
• mRNA Refseq: NM_001033126
• Protein Refseq: NP_001028298
• UniProt ID: P41272
• Chromosome Location: 6 F3; 6 60.35 cM
• Pathway: Cytokine-cytokine receptor interaction
• Function: protein binding; receptor activity