Recombinant Mouse Calca protein, His & GST-tagged

• Cat.No.: Calca-795M
• Product Overview: Recombinant Mouse Calca aa. (Val26~Asn136 (Accession # P70160)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Mouse
• Source: E.coli
• Tag: GST&His
• Protein Length: Val26~Asn136
• Description: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 44.3kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Calca calcitonin/calcitonin-related polypeptide, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Calca
• Synonyms: CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin gene-related peptide 1
• Gene ID: 12310
• mRNA Refseq: NM_001033954.3
• Protein Refseq: NP_001029126.1
• UniProt ID: P70160