Recombinant Mouse Bmpr2 Protein, MYC/DDK-tagged

• Cat.No.: Bmpr2-715M
• Product Overview: Purified recombinant protein of full-length mouse bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension.
• Molecular Mass: 115.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) [ Mus musculus (house mouse) ]
• Official Symbol: Bmpr2
• Synonyms: Bmpr2; bone morphogenetic protein receptor, type II (serine/threonine kinase); BMP-2; BRK-3; BMPR-2; BMPRII; BMPR-II; Gm20272; AL117858; AW546137; BB189135; 2610024H22Rik; bone morphogenetic protein receptor type-2; BMP type II receptor; BMP type-2 receptor; bone morphogenic protein receptor, type II (serine/threonine kinase); EC 2.7.11.30
• Gene ID: 12168
• mRNA Refseq: NM_007561
• Protein Refseq: NP_031587
• UniProt ID: O35607