Recombinant Mouse Bmp2 protein, His/S-tagged

• Cat.No.: Bmp2-211M
• Product Overview: Recombinant Mouse Bmp2 fused with His/S tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His&S
• Description: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.
• Form: Lyophilized from sterile PBS, pH 7.4
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Store at -70 centigrade. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: Bmp2 bone morphogenetic protein 2 [ Mus musculus ]
• Official Symbol: Bmp2
• Synonyms: BMP2; bone morphogenetic protein 2; BMP-2; BMP-2A; bone morphogenetic protein 2A; Bmp2a; AI467020
• Gene ID: 12156
• mRNA Refseq: NM_007553
• Protein Refseq: NP_031579
• UniProt ID: P21274
• Chromosome Location: 2 F2; 2 65.21 cM
• Pathway: Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem
• Function: BMP receptor binding; SMAD binding; cytokine activity; growth factor activity; phosphatase activator activity; protein binding; protein domain specific binding; protein heterodimerization activity; protein homodimerization activity; receptor binding; retinol dehydrogenase activity