Recombinant Mouse Blmh Protein, His-tagged

• Cat.No.: Blmh-419M
• Product Overview: Recombinant Mouse Blmh(Ala27~Cys164) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: The encoded protein is a cytoplasmic cysteine peptidase involved in inactivation of bleomycin, a glycopeptide which is a component of combination chemotherapy regimens for cancer. This encoded enzyme is highly conserved, and it contains the signature active site residues of cysteine protease papain superfamily enzymes. It is postulated that this enzyme has protective effects against bleomycin-induced pulmonary fibrosis and bleomycin tumor resistance.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 21.8kDa
• Protein length: Ala27~Cys164
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: Blmh bleomycin hydrolase [ Mus musculus ]
• Official Symbol: Blmh
• Synonyms: BLMH; bleomycin hydrolase; BLM hydrolase; Bh; Bmh; AI035728; MGC36899; MGC37104; MGC39026
• Gene ID: 104184
• mRNA Refseq: NM_178645
• Protein Refseq: NP_848760