Recombinant Mouse Arpc5 Protein, Myc/DDK-tagged

• Cat.No.: Arpc5-1727M
• Product Overview: Purified recombinant protein of mouse full-length actin related protein 2/3 complex, subunit 5 (Arpc5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
• Molecular Mass: 16.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arpc5 actin related protein 2/3 complex, subunit 5 [ Mus musculus (house mouse) ]
• Official Symbol: Arpc5
• Synonyms: ARPC5; actin related protein 2/3 complex, subunit 5; actin-related protein 2/3 complex subunit 5; arp2/3 complex 16 kDa subunit; p16-Arc; 5830443F10Rik
• Gene ID: 67771
• mRNA Refseq: NM_026369
• Protein Refseq: NP_080645
• UniProt ID: Q9CPW4