Recombinant Mouse Arl6ip1 Protein, Myc/DDK-tagged

• Cat.No.: Arl6ip1-1710M
• Product Overview: Purified recombinant protein of mouse full-length ADP-ribosylation factor-like 6 interacting protein 1 (Arl6ip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity-dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates and downstream markers of apoptosis but not CASP9 itself. May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 23.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arl6ip1 ADP-ribosylation factor-like 6 interacting protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Arl6ip1
• Synonyms: ARL6IP1; ADP-ribosylation factor-like 6 interacting protein 1; ADP-ribosylation factor-like protein 6-interacting protein 1; ARL-6-interacting protein 1; ADP-ribosylation-like factor 6 interacting protein; AIP-6; ARMER; Aip-1; Arl6ip; C85138; AL022945; AU042858; mKIAA0069
• Gene ID: 54208
• mRNA Refseq: NM_019419
• Protein Refseq: NP_062292
• UniProt ID: Q9JKW0