Recombinant Mouse Anp32e Protein, Myc/DDK-tagged

• Cat.No.: Anp32e-1645M
• Product Overview: Purified recombinant protein of mouse full-length acidic (leucine-rich) nuclear phosphoprotein 32 family, member E (Anp32e), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 30.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Anp32e acidic (leucine-rich) nuclear phosphoprotein 32 family, member E [ Mus musculus (house mouse) ]
• Official Symbol: Anp32e
• Synonyms: ANP32E; acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; acidic leucine-rich nuclear phosphoprotein 32 family member E; LANP-like protein; cerebellar postnatal development protein 1; CPD1; LANPL; LANP-L; mLANP-L; AI047746; AI326868; 2810018A15Rik; MGC11640
• Gene ID: 66471
• mRNA Refseq: NM_023210
• Protein Refseq: NP_075699
• UniProt ID: P97822