Recombinant Mouse Amot Protein, Myc/DDK-tagged

• Cat.No.: Amot-1613M
• Product Overview: Purified recombinant protein of mouse full-length angiomotin (Amot), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
• Molecular Mass: 120.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Amot angiomotin [ Mus musculus (house mouse) ]
• Official Symbol: Amot
• Synonyms: AMOT; angiomotin; Sii6; CAG-2; C81439; D0Kist1; mKIAA1071; E230009N18Rik
• Gene ID: 27494
• mRNA Refseq: NM_153319
• Protein Refseq: NP_695231
• UniProt ID: Q8VHG2