Recombinant Mouse Agbl5 Protein, Myc/DDK-tagged

• Cat.No.: Agbl5-1552M
• Product Overview: Purified recombinant protein of mouse full-length ATP/GTP binding protein-like 5 (cDNA clone MGC:67138 IMAGE:6813901), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 79.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Agbl5 ATP/GTP binding protein-like 5 [ Mus musculus (house mouse) ]
• Official Symbol: Agbl5
• Synonyms: Agbl5; ATP/GTP binding protein-like 5; Ccp; CCP5; 9430057O19Rik; cytosolic carboxypeptidase-like protein 5; carboxypeptidase 5, cytosolic; EC 3.4.17.-
• Gene ID: 231093
• mRNA Refseq: NM_174849
• Protein Refseq: NP_777274
• UniProt ID: Q09M02