Recombinant Mouse Acadl Protein, His&GST-tagged

• Cat.No.: Acadl-22M
• Product Overview: Recombinant Mouse Acadl Protein (Ile204-Ser430) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a homotetrameric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-double bond in a FAD-dependent reaction. As beta-oxidation cycles through its four steps, each member of the acyl-CoA dehydrogenase family works at an optimum fatty acid chain-length. This enzyme has its optimum length between C12- and C16-acylCoA. In mice, deficiency of this gene can cause sudden death, cardiomyopathy as well as fasting and cold intolerance.
• Source: E. coli
• Species: Mouse
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 55.7 kDa
  Accurate Molecular Mass: 56 kDa
• Protein length: Ile204-Ser430
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Acadl acyl-Coenzyme A dehydrogenase, long-chain [ Mus musculus (house mouse) ]
• Official Symbol: Acadl
• Synonyms: ACADL; acyl-Coenzyme A dehydrogenase, long-chain; long-chain specific acyl-CoA dehydrogenase, mitochondrial; acetyl-Coenzyme A dehydrogenase, long-chain; LCAD; C79855; AA960361; AU018452
• Gene ID: 11363
• mRNA Refseq: NM_007381
• Protein Refseq: NP_031407
• UniProt ID: P51174