Recombinant Mouse Abcd4, His-tagged
| Cat.No. : | Abcd4-3738M |
| Product Overview : | ATP-binding cassette sub-family D member 4 (Abcd4) |
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| Description : | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that the human protein may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. |
| Source : | E. Coli or Yeast |
| Species : | Mouse |
| Tag : | His |
| Form : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
| Protein length : | 606 |
| Purity : | >90% |
| Notes : | Small volumes of Abcd4 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
| Storage : | Store at -20 degree C. For extended storage, store at -20 or -80 degree C. |
| Storage Buffer : | PBS pH 7.4, 50% glycerol |
| Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name | Abcd4 |
| Official Symbol | Abcd4 |
| Synonyms | Abcd4; Pxmp1l ; Abcd4; Abcd4; P69r; P70R... |
| Gene ID | 19300 |
| mRNA Refseq | NM_008992.2 |
| Protein Refseq | NP_033018.2 |
| UniProt ID | O89016 |
| Chromosome Location | Chromosome: 12; NC_000078.6 (84602531..84617466, complement). Location: 12 D1; 12 39.3 cM |
| Function | modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis |
Not For Human Consumption!
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