Recombinant Macaca mulatta Interleukin 8

• Cat.No.: IL8-5434M
• Product Overview: Recombinant RhesusMonkey IL8 is expressed in E. coli.

Specification

• Species: Macaca mulatta
• Source: E.coli
• Tag: Non
• Description: IL8, also named CXCL8, monocyte-derivedneutrophil chemotactic factor (MDNCF), neutrophil-activating protein 1(NAP1), neutrophil-activating factor (NAF) and granulocyte chemotacticpeptide (GCP), belongs to the Glu-Leu-Arg motif containing (ELR+)CXC chemokine family and has been designated CXCL8. IL8 is a potentneutrophil chemoattractant that recruits neutrophils to sites ofinflammation. IL8 also activates neutrophil functions and promotesangiogenesis.
• Form: Lyophilized from a0.2µm filtered concentrated solution in PBS, pH 7.4.
• MolecularWeight: Approximately 9.1kDa, a single non-glycosylated polypeptide chain containing 79 amino acids.
• Purity: > 97% by SDS-PAGEand HPLC analyses
• Endotoxin Level: Less than 1EU/µg ofrRh IL8 as determined by LAL method.
• Biological Activity: Determined by itsability to chemoattract human peripheral blood neutrophils using aconcentration range of 25-150 ng/ml.
• Sequences: AVLPRSAKELRCECIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE PWVQRVVEKF VKRAENQNP
• Reconstitution: We recommend thatthis vial be briefly centrifuged prior to opening to bring the contents tothe bottom. Reconstitute in sterile distilled water or aqueous buffercontaining 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutionsshould be apportioned into working aliquots and stored at ≤-20°C. Furtherdilutions should be made in appropriate buffered solutions.
• Storage: This lyophilizedpreparation is stable at 2-8°C, but should be kept at -20°C for long termstorage, preferably desiccated. Upon reconstitution, the preparation isstable for up to one week at 2-8°C. For maximal stability, apportion thereconstituted preparation into working aliquots and store at -20°C to -80°C.Avoid repeated freeze/thaw cycles.
• OfficialSymbol: IL8

Gene Information

• Gene Name: IL8 interleukin 8 [ Macacamulatta ]
• Synonyms: IL8; interleukin 8;interleukin-8; IL-8; C-X-C motif chemokine 8
• Gene ID: 613028
• mRNA Refseq: NM_001032965
• Protein Refseq: NP_001028137
• UniProt ID: P67813
• Chromosome Location: 5
• Pathway: Amoebiasis; Bladder cancer; Chemokinesignaling pathway; Cytokine-cytokine receptor interaction; Hepatitis C; HepatitisA; Legionellosis; Malaria; NOD-like receptor signaling pathway; Pathways incancer; Pertussis; RIG-I-like receptor signaling pathway; Rheumatoidarthritis; Salmonella infection; Toll-like receptor signaling pathway