Recombinant Human YEATS Domain Containing 4, His-tagged

• Cat.No.: YEATS4-4834H
• Product Overview: Recombinant human YEATS4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: YEATS4 has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing30% glycerol, 2mM DTT, 0.2M NaCl, 0.1mM PMSF.
• Molecular Weight: 28.9 kDa (250aa), confirmed by MALDI-TOF.
• Purity: >90% by SDS-PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSMFKRMAE FGPDSGGRVK GVTIVKPIVY GNVARYFGKK REEDGHTHQW TVYVKPYRNE DMSAYVKKIQFKLHESYGNP LRVVTKPPYE ITETGWGEFE IIIKIFFIDP NERPVTLYHL LKLFQSDTNA MLGKKTVVSE FYDEMIFQDP TAMMQQLLTTSRQLTLGAYK HETEFAELEV KTREKLEAAK KKTSFEIAEL KERLKASRET INCLKNEIRK LEEDDQAKDI
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: C-MYB transcription factor network

Gene Information

• Gene Name: YEATS4 YEATS domain containing 4 [ Homo sapiens ]
• Official Symbol: YEATS4
• Synonyms: YEATS4; YEATS domain containing 4; YAF9; GAS41; NUBI-1; 4930573H17Rik; B230215M10Rik; NuMA binding protein 1; glioma-amplified sequence-41; YEATS domain-containing protein 4; nuBI1; nuMA-binding protein 1; glioma-amplified sequence 41; nuBI1; Glioma-amplified sequence 41; NuMA-binding protein 1; 4930573H17Rik; NuBI1; B230215M10Rik
• Gene ID: 8089
• mRNA Refseq: NM_006530
• Protein Refseq: NP_006521
• MIM: 602116
• UniProt ID: O95619
• Chromosome Location: 12q13-q15
• Function: protein C-terminus binding; protein C-terminus binding; transcription factor activity