Recombinant Human WEE1 protein, MYC/DDK-tagged
Cat.No. : | WEE1-36H |
Product Overview : | Recombinant Human WEE1, transcript variant 1, fussed with MYC/DDK at C-terminal was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 71.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | WEE1 WEE1 G2 checkpoint kinase [ Homo sapiens ] |
Official Symbol | WEE1 |
Synonyms | WEE1A; WEE1hu; wee1-like protein kinase; WEE1 homolog; WEE1+ homolog; wee1A kinase |
Gene ID | 7465 |
mRNA Refseq | NM_003390 |
Protein Refseq | NP_003381 |
MIM | 193525 |
UniProt ID | P30291 |
Chromosome Location | 11p15.4 |
Pathway | Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell cycle - G2/M transition, conserved biosystem |
Function | ATP binding; magnesium ion binding; non-membrane spanning protein tyrosine kinase activity |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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