Recombinant Human WDR12, MYC/DDK-tagged

• Cat.No.: WDR12-49H
• Product Overview: Recombinant Human WDR12, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.
• Molecular Mass: 47.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: WDR12 WD repeat domain 12 [ Homo sapiens ]
• Official Symbol: WDR12
• Synonyms: WDR12; WD repeat domain 12; ribosome biogenesis protein WDR12; FLJ10881; YTM1; FLJ10881; FLJ12719; FLJ12720; OTTHUMP00000163754; Ribosome biogenesis protein WDR12; WD repeat containing protein 12; WD repeat domain 12; WD repeat-containing protein 12; WDR 12; Wdr12; WDR12_HUMAN; YTM1; WD repeat-containing protein 12
• Gene ID: 55759
• mRNA Refseq: NM_018256
• Protein Refseq: NP_060726
• UniProt ID: Q9GZL7
• Chromosome Location: 2q33.2
• Pathway: Delta-Notch Signaling Pathway
• Function: protein binding; ribonucleoprotein complex binding