Recombinant Human VRK3

• Cat.No.: VRK3-31742TH
• Product Overview: Recombinant full lengthhuman VRK3 protein, 55 kDa.

Specification

• Description: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Tag: Non
• Full Length: Full L.

Gene Information

• Gene Name: VRK3 vaccinia related kinase 3 [ Homo sapiens ]
• Official Symbol: VRK3
• Synonyms: VRK3; vaccinia related kinase 3; inactive serine/threonine-protein kinase VRK3
• Gene ID: 51231
• mRNA Refseq: NM_001025778
• Protein Refseq: NP_001020949
• Uniprot ID: Q8IV63
• Chromosome Location: 19q13.33
• Function: ATP binding; nucleotide binding; protein kinase activity; protein phosphatase binding; transferase activity, transferring phosphorus-containing groups