Recombinant Human VLDLR protein, His & T7-tagged

• Cat.No.: VLDLR-5719H
• Product Overview: Recombinant Human VLDLR aa. (Lys418~Ala722 (Accession # P98155)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Lys418~Ala722
• Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 38.2kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.9.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: VLDLR very low density lipoprotein receptor [ Homo sapiens (human) ]
• Official Symbol: VLDLR
• Synonyms: VLDLR; very low density lipoprotein receptor; CAMRQ1; CARMQ1; CHRMQ1; VLDL-R; VLDLRCH; very low-density lipoprotein receptor; VLDL receptor
• Gene ID: 7436
• mRNA Refseq: NM_001018056.2
• Protein Refseq: NP_001018066.1
• UniProt ID: P98155