Recombinant Human VCAM1, His-tagged

• Cat.No.: VCAM1-31199TH
• Product Overview: Recombinant fragment corresponding to amino acids 109-331 of Human VCAM1 with an amino-terminal hexahistidine tag; 203 amino acids, 25kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 109-331 a.a.
• Description: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
• Conjugation: HIS
• Tissue specificity: Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 1x Laemmli Buffer (2.5% Glycerol, 1% SDS, 0.1% Bromophenol blue, 50mM DTT, 25mM Tris HCl, pH 6.8)
• Storage: Store at -20°C. Stable for 12 months at -20°C
• Sequence Similarities: Contains 7 Ig-like C2-type (immunoglobulin-like) domains.

Gene Information

• Gene Name: VCAM1 vascular cell adhesion molecule 1 [ Homo sapiens ]
• Official Symbol: VCAM1
• Synonyms: VCAM1; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; CD106
• Gene ID: 7412
• mRNA Refseq: NM_001078
• Protein Refseq: NP_001069
• MIM: 192225
• Uniprot ID: P19320
• Chromosome Location: 1p32-p31
• Pathway: Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem
• Function: cell adhesion molecule binding; cell adhesion molecule binding; integrin binding