Recombinant Human Vascular Endothelial Growth Factor C, His-tagged
Cat.No. : | VEGFC-615H |
Product Overview : | The recombinant human protein contains N-terminal and C-terminal His-tags (167 aa, MW 18.772 kDa). |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Description : | The recombinant VEGFC (Vascular Endothelial Growth Factor-C) lacks the N-terminal signal peptide and includes amino acids from T103 to R227 of Gene Bank U58111. |
Biological Activity : | Activity of VEGFC is tested by the stimulation of VEGF-R3 phosphorylation in cells transfected with VEGF-R3. The expected ED50 is > 200 ng/ml. |
Molecular Weight : | 18.772 kDa |
Form : | Lyophilized without additives. |
Appearance : | Lyophilized protein |
Endotoxin Level : | <0.1 ng/μg |
Reconstitution : | We recommend a quick spin followed by reconstitution in 0.1% acetic acid to a concentration of 0.1-1.0 mg/ml. The solution should be stored at -70°C. |
Purity : | >90% by SDS-PAGE analyses. |
Storage : | The lyophilized VEGFC is best-stored at -20°C. Reconstituted VEGFC should be stored in working aliquots at -70°C. |
Pathways : | Bladder cancer; Cytokine-cytokine receptor interaction; Focal Adhesion; Focal adhesion; Formation of Platelet plug; Heart Development; Hemostasis; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; Response to elevated platelet cytosolic Ca2+; Signaling by VEGF; Signaling events mediated by VEGFR1 and VEGFR2; VEGF ligand-receptor interactions; VEGFR3 signaling in lymphatic endothelium; mTOR signaling pathway |
Gene Name | VEGFC vascular endothelial growth factor C [ Homo sapiens ] |
Official Symbol | VEGFC |
Synonyms | VEGFC; vascular endothelial growth factor C; RP; Flt4-L; VEGF-C; FLT4 ligand DHM; OTTHUMP00000218843; vascular endothelial growth factor-related protein; VRP; Flt4 ligand |
Gene ID | 7424 |
mRNA Refseq | NM_005429 |
Protein Refseq | NP_005420 |
MIM | 601528 |
UniProt ID | P4976 |
Chromosome Location | 4q34.3 |
Function | chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding |
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Not For Human Consumption!
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