Recombinant Human Vascular Endothelial Growth Factor C

• Cat.No.: VEGFC-641H
• Product Overview: Recombinant human VEGFC proteinwas expressed in HEK 293 cells.

Specification

• Species: Human
• Source: Human
• Tag: Non
• Description: VEGFC, a member ofthe VEGF/PDGF family of structurally related proteins, is a potent antigeniccytokine. It promotes endothelial cell growth, promotes lymphangiogesis, andcan also affect vascular permeability. VEGFC is expressed in various tissues,but is not produced in peripheral blood lymphocytes. During embryogenesis, VEGFCmay play a role in the formation of the venous and lymphatic vascularsystems.
• Form: Suppliedas a lyophilized powder.
• Purity: > 95% pure by SDSPAGE and HPLC
• Sequence: Region of VEGFCprotein corresponding to amino acids: MAHYNTEILK SIDNEWRKTQ CMPREVCIDVGKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY LSKTLFEITV PLSQGPKPVT ISFANHTSCRCMSKLDVYRQ VHSIIRR
• Applications: Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions.
• Storage: Storeat 4 deg C until reconstitution. Following reconstitution aliquot and freezeat -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: VEGFC

Gene Information

• Gene Name: VEGFC vascular endothelialgrowth factor C [ Homo sapiens ]
• Synonyms: VEGFC; vascularendothelial growth factor C; VRP; Flt4-L; Vascular endothelialgrowth factor C; VEGF-C; Flt4ligand; Vascular endothelial growth factor-related protein; FLT4 ligand DHM
• Gene ID: 7424
• mRNA Refseq: NM_005429
• Protein Refseq: NP_005420
• MIM: 601528
• UniProt ID: P49767
• Chromosome Location: 4q34.3
• Pathway: Cytokine-cytokine receptorinteraction; Focal adhesion; Pancreatic cancer; Renal cell carcinoma; mTORsignaling pathway; Hemostasis; Signaling by VEGF
• Function: chemoattractant activity; growth factor activity; protein binding; vascularendothelial growth factor receptor binding