Recombinant Human Vascular Cell Adhesion Molecule 1

• Cat.No.: VCAM1-1695H

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Non
• Description: Vascular cell adhesion molecule 1, also known as VCAM1 is an immunoglobulin-like adhesion molecule expressed on activated endothelial cells. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. VCAM-1 promotes the adhesion of lymphocytes, monocytes, eosinophils, and basophils.
• Molecular Weight: The predicted molecular weight of Recombinant Human VCAM-1 is Mr 74 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 90-95 kDa.
• State Of Matter: Lyophilized.
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: VCAM1 vascular cell adhesion molecule 1 [ Homo sapiens ]
• Synonyms: VCAM1; vascular cell adhesion molecule 1; INCAM-100; Vascular cell adhesion protein 1 precursor; CD-106 antigen; CD106; DKFZp779G2333; MGC99561; vascular cell adhesion molecule 1; CD106 antigen; OTTHUMP00000012650; OTTHUMP00000012651; L1CAM; V-CAM 1
• Gene ID: 7412
• mRNA Refseq: NM_001078
• Protein Refseq: NP_001069
• MIM: 192225
• UniProt ID: P19320
• Chromosome Location: 1p32-p31
• Pathway: Cell adhesion molecules (CAMs); Leukocyte transendothelial migration; Signaling in Immune system
• Function: integrin binding; protein binding