Recombinant Human VAMP1

• Cat.No.: VAMP1-215H
• Product Overview: Recombinant Human VAMP1 produced inE.Coliis a single, non-glycosylated polypeptide chain. The protein contains 111 amino acids and has a molecular mass of 11.9 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Synaptobrevin 1 (Vehicle-associated membrane, VAMP1) is one of the key proteins in the SNARE complex which is involved in regulated exocytosis. Synaptobrevin1 binds to t-SNAREs, syntaxin (STX) and SNAP25, after the fusion of synaptic vesicles to plasma membrane.
• Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSAPAQPPAE GTEGTAPGGG PPGPPPNMTS NRRLQQTQAQVEEVVDIIRV NVDKVLERDQ KLSELDDRAD ALQAGASQFE SSAAKLKRKY W.
• Physical Appearance: Sterile Filtered colorless solution.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Formulation: The protein solution (1mg/ml) contains 1X PBS and 1mM EDTA.
• Stability: Synaptobrevin although stable 14°Cfor 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) [ Homo sapiens ]
• Synonyms: VAMP1; vesicle-associated membrane protein 1 (synaptobrevin 1); SYB1; VAMP-1; DKFZp686H12131; Synaptobrevin-1; vesicle-associated membrane protein 1; synaptobrevin 1
• Gene ID: 6843
• mRNA Refseq: NM_014231
• Protein Refseq: NP_055046
• UniProt ID: P23763
• Chromosome Location: 12p
• MIM: 185880
• Pathway: SNARE interactions in vesicular transport; Botulinum neurotoxicity
• Function: protein binding