Recombinant Human USP5 Protein, MYC/DDK-tagged

• Cat.No.: USP5-681H
• Product Overview: Recombinant human USP5 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 93.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ubiquitin specific peptidase 5[ Homo sapiens ]
• Official Symbol: USP5
• Synonyms: ISOT
• Gene ID: 8078
• Protein Refseq: NP_003472
• MIM: 601447
• UniProt ID: P45974