Recombinant Human USP1, MYC/DDK-tagged

• Cat.No.: USP1-955H
• Product Overview: Recombinant Human USP1 fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.
• Molecular Mass: 88 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Storage buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage: Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• OfficialSymbol: USP1

Gene Information

• Gene Name: USP1 ubiquitin specific peptidase 1 [ Homo sapiens ]
• Synonyms: USP1; ubiquitin specific peptidase 1; ubiquitin specific protease 1; ubiquitin carboxyl-terminal hydrolase 1; Deubiquitinating enzyme 1; hUBP; Ubiquitin carboxyl terminal hydrolase 1; Ubiquitin carboxyl-terminal hydrolase 1; Ubiquitin specific peptidase 1; Ubiquitin thiolesterase 1; Ubiquitin-specific-processing protease 1; UBP; UBP1_HUMAN; USP 1; Usp1; hUBP; ubiquitin thioesterase 1; deubiquitinating enzyme 1; ubiquitin thiolesterase 1; ubiquitin carboxyl terminal hydrolase 1; ubiquitin specific processing protease 1; ubiquitin-specific-processing protease 1; UBP
• Gene ID: 7398
• mRNA Refseq: NM_001017415
• Protein Refseq: NP_001017415
• MIM: 603478
• UniProt ID: O94782
• Chromosome Location: 1p31.3
• Pathway: DNA Repair; Fanconi Anemia pathway; Fanconi anemia pathway; Fanconi anemia pathway; Regulation of the Fanconi anemia pathway
• Function: cysteine-type endopeptidase activity; peptidase activity; protein binding; ubiquitin thiolesterase activity; ubiquitin-specific protease activity