Recombinant Human ULBP2 Protein, GST-His-tagged

• Cat.No.: ULBP2-433H
• Product Overview: Recombinant Human ULBP2 fused with N-terminal GST and C-terminal His was expressed in E. coli.

Specification

• Description: This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 53.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ULBP2 UL16 binding protein 2 [ Homo sapiens ]
• Official Symbol: ULBP2
• Synonyms: ULBP2; UL16 binding protein 2; NKG2D ligand 2; RAET1H; N2DL-2; NKG2DL2; ALCAN-alpha; UL16-binding protein 2; retinoic acid early transcript 1H; retinoic acid early transcript 1 H; N2DL2
• Gene ID: 80328
• mRNA Refseq: NM_025217
• Protein Refseq: NP_079493
• MIM: 605698
• UniProt ID: Q9BZM5