Recombinant Human UBTF Protein, MYC/DDK-tagged

• Cat.No.: UBTF-478H
• Product Overview: Recombinant human UBTF protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 84.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: upstream binding transcription factor, RNA polymerase I [ Homo sapiens ]
• Official Symbol: UBTF
• Synonyms: NOR-90; UBF; UBF-1; UBF1; UBF2
• Gene ID: 7343
• mRNA Refseq: NM_001076683.1
• Protein Refseq: NP_001070151.1
• MIM: 600673
• UniProt ID: P17480