Recombinant Human UBLCP1, His-tagged

• Cat.No.: UBLCP1-44H
• Product Overview: Recombinant human UBLCP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: UBLCP1 also known as ubiquitin-like domain-containing CTD phosphatase 1. This protein dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT
• Molecular Mass: 39.2kDa (341aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMALPIIV KWGGQEYSVT TLSEDDTVLD LKQFLKTLTG VLPERQKLLG LKVKGKPAEN DVKLGALKLK PNTKIMMMGT REESLEDVLG PPPDNDDVVN DFDIEDEVVE VENREENLLK ISRRVKEYKV EILNPPREGK KLLVLDVDYT LFDHRSCAET GVELMRPYLH EFLTSAYEDY DIVIWSATNM KWIEAKMKEL GVSTNANYKI TFMLDSAAMI TVHTPRRGLI DVKPLGVIWG KFSEFYSKKN TIMFDDIGRN FLMNPQNGLK IRPFMKAHLN RDKDKELLKL TQYLKEIAKL DDFLDLNHKY WERYLSKKQG Q
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 [ Homo sapiens ]
• Official Symbol: UBLCP1
• Synonyms: UBLCP1; ubiquitin-like domain containing CTD phosphatase 1; ubiquitin-like domain-containing CTD phosphatase 1; CPUB1; CTD phosphatase like with ubiquitin domain 1; MGC10067; nuclear proteasome inhibitor UBLCP1; CTD phosphatase-like with ubiquitin domain 1; CTD-like phosphatase domain-containing protein; FLJ25267
• Gene ID: 134510
• mRNA Refseq: NM_145049
• Protein Refseq: NP_659486
• MIM: 609867
• UniProt ID: Q8WVY7
• Chromosome Location: 5q33.3
• Function: hydrolase activity; phosphoprotein phosphatase activity