Recombinant Human Ubiquitin-Like 4A, His-tagged

• Cat.No.: UBL4A-5553H
• Product Overview: Recombinant human UBL4A protein, fused to His-tag at C-terminus,was expressed in E.coli and purified by using conventionalchromatography techniques.

Specification

• Species: Human
• Tag: His
• Description: UBL4A,also known as GDX, contains 1 ubiquitin-like domain. Post-translationalmodification by ubiquitin and ubiquitin-related proteins plays critical rolesin protein degradation and in regulation of essential cellular processes. Inmammals, transcription grinds to a halt during late spermiogenesis due tocompaction of the spermatid genome, which creates a special need for robustpost-transcriptional regulation. UBL4A plays any role in targeting cellularproteins for degradation.
• Form: Liquid.In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,10% glycerol, 100mM NaCl.
• Molecular Weight: 18.8kDa (165aa),confirmed by MALDI-TOF.
• Purity: > 95%by SDS - PAGE
• Concentration: 1mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MQLTVKALQGRECSLQVPED ELVSTLKQLV SEKLNVPVRQ QRLLFKGKAL ADGKRLSDYS IGPNSKLNLV VKPLEKVLLEEGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQLQ RDYERSLSRL TLDDIERLAS RFLHPEVTETMEKGFSKLEH HHHHH
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: UBL4A ubiquitin-like 4A [ Homosapiens ]
• Official Symbol: UBL4A
• Synonyms: UBL4A;ubiquitin-like 4A; GDX; G6PD; GET5; MDY2; UBL4; TMA24; DX254E;DXS254E; ubiquitin-likeprotein 4A; ubiquitin-like 4; ubiquitin-like protein GDX; Ubiquitin-likeprotein 4A; Ubiquitin-like protein GDX
• Gene ID: 8266
• mRNA Refseq: NM_014235
• Protein Refseq: NP_055050
• MIM: 312070
• UniProt ID: P11441
• Chromosome Location: Xq28
• Function: small conjugatingprotein ligase activity