Recombinant Human ubiquitin B

• Cat.No.: UBB-28H
• Product Overview: Recombinant human Ubiquitin(76amino acid) was overexpressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Ubiquitin is a small protein that is composed of 76 amino acids and its sequence is highly conserved throughout evolution from invertebrates to mammals. In the cytoplasm, ubiquitin is involved in ATP-dependent nonlysomal proteolysis of various proteins. In the nucleus, ubiquitin is conjugated to histone2A and may play a role in regulation of chromatin structure and/or regulation of transcriptional activity.
• Form: Liquid. In 50 mM HEPES buffer (pH 7.5) containing 150 mM NaCl 10% glycerol
• Purity: > 95% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGG
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Parkinson"s disease; Apoptosis; Cell Cycle Checkpoints; Cell Cycle, Mitotic; DNA Replication; HIV Infection; Signaling by EGFR; Signaling by Wnt; Signaling in Immune system; Signalling by NGF

Gene Information

• Gene Name: UBB ubiquitin B [ Homo sapiens ]
• Synonyms: FLJ25987; MGC8385; OTTHUMP00000064960; OTTHUMP00000064961; UBA80; UBCEP1; UBCEP2; polyubiquitin B; ubiquitin B; UBB; polyubiquitin B.
• Gene ID: 7314
• mRNA Refseq: NM_018955
• Protein Refseq: NP_061828
• MIM: 191339
• UniProt ID: P62988
• Chromosome Location: 17p12-p11.2
• Function: protein binding; transcription regulator activity