Recombinant Human UBE2Z, His-tagged

Cat.No. : UBE2Z-211H
Product Overview : Recombinant human UBE2Z (USE1) (109-end) was expressed in E. coli cells using an N-terminal His tag.
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Description : UBE2Z(USE1) encodes the ubiquitin conjugating enzyme (E2) which is involved in Ubiquitination, the covalent attachment of the protein ubiquitin (Ub) to other cellular proteins. UBE2Z plays an important role in the ubiquitin process and has been implicated in a number of important physiological processes including apoptosis. UBE2Z is specifically charged with ubiquitin by UBA6. UBE2Z is widely expressed in human tissues and expression is especially high in placenta, pancreas, spleen and testis.
Source : E. coli
Species : Human
Tag : His
Form : Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Molecular Mass : ~30 kDa
Purity : >80% by densitometry
Applications : Western Blot
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 μg/μl
Protein length : 109-end a.a.
Gene Name UBE2Z ubiquitin-conjugating enzyme E2Z [ Homo sapiens ]
Official Symbol UBE2Z
Synonyms UBE2Z; ubiquitin-conjugating enzyme E2Z; ubiquitin-conjugating enzyme E2 Z; FLJ13855; UBA6 specific enzyme E2; USE1; UBA6-specific enzyme E2; ubiquitin-protein ligase Z; ubiquitin carrier protein Z; uba6-specific E2 conjugating enzyme 1; HOYS7;
Gene ID 65264
mRNA Refseq NM_023079
Protein Refseq NP_075567
MIM 611362
UniProt ID Q9H832
Chromosome Location 17q21.32
Pathway Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem;
Function ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; ubiquitin-protein ligase activity;

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