Recombinant Human TPBG Protein, C-Avi-6His tagged, Biotinylated
Cat.No. : | TPBG-26H |
Product Overview : | Biotinylated Recombinant Human Trophoblast Glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a Avi, 6His tag at the C-terminus. |
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Species : | Human |
Source : | Human Cells |
Tag : | Avi&His |
Protein Length : | Ser32-Ser355 |
Description : | Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Shipping : | Ambient |
Gene Name | TPBG trophoblast glycoprotein [ Homo sapiens (human) ] |
Official Symbol | TPBG |
Synonyms | TPBG; 5T4; 5T4AG; M6P1; WAIF1 |
Gene ID | 7162 |
mRNA Refseq | NM_001166392 |
Protein Refseq | NP_001159864 |
MIM | 190920 |
UniProt ID | Q13641 |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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