Recombinant Human TPBG Protein, C-Avi-6His tagged, Biotinylated

Cat.No. : TPBG-26H
Product Overview : Biotinylated Recombinant Human Trophoblast Glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a Avi, 6His tag at the C-terminus.
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Species : Human
Source : Human Cells
Tag : Avi&His
Protein Length : Ser32-Ser355
Description : Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Shipping : Ambient
Gene Name TPBG trophoblast glycoprotein [ Homo sapiens (human) ]
Official Symbol TPBG
Synonyms TPBG; 5T4; 5T4AG; M6P1; WAIF1
Gene ID 7162
mRNA Refseq NM_001166392
Protein Refseq NP_001159864
MIM 190920
UniProt ID Q13641

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