Recombinant Human TOR1AIP2 protein, His & T7-tagged

• Cat.No.: TOR1AIP2-1572H
• Product Overview: Recombinant Human TOR1AIP2 aa. (Thr249~Leu475) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.9kDa
• Protein length: Thr249~Leu475
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 6

Gene Information

• Gene Name: TOR1AIP2 torsin 1A interacting protein 2 [ Homo sapiens (human) ]
• Official Symbol: TOR1AIP2
• Synonyms: TOR1AIP2; torsin 1A interacting protein 2; NET9; LULL1; IFRG15; torsin-1A-interacting protein 2; interferon alpha responsive protein; 15 kDa interferon-responsive protein; interferon responsive gene 15; lumenal domain like LAP1; torsin A interacting protein 2
• Gene ID: 163590
• mRNA Refseq: NM_001199260.1
• Protein Refseq: NP_001186189.1
• UniProt ID: Q8NFQ8