Recombinant Human TNNC2 protein, His & GST-tagged

• Cat.No.: TNNC2-7941H
• Product Overview: Recombinant Human TNNC2 aa. (Thr2~Gln160 (Accession # P02585)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: 45 kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Thr2~Gln160
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 4.7.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: TNNC2 troponin C2, fast skeletal type [ Homo sapiens (human) ]
• Official Symbol: TNNC2
• Synonyms: TNNC2; troponin C2, fast skeletal type; troponin C, skeletal muscle; troponin C type 2 (fast)
• Gene ID: 7125
• mRNA Refseq: NM_003279.2
• Protein Refseq: NP_003270.1
• UniProt ID: P02585