Recombinant Human TNFSF13B protein, His & Fc-tagged

• Cat.No.: TNFSF13B-445H
• Product Overview: Recombinant Human TNFSF13B (Q9Y275) aa. (Ala134~Leu285) fused with His & Fc tag was produced in HEK293F cells.

Specification

• Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
• Source: HEK293F
• Species: Human
• Tag: His&Fc
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 43.9kDa; Accurate Molecular Mass: 44kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Ala134~Leu285
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Characteristic: Isoelectric point is 4.9.
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; EMSA; Reporter Assays; Purification; Amine Reactive Labeling
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200ug/mL
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: TNFSF13B TNF superfamily member 13b [ Homo sapiens (human) ]
• Official Symbol: TNFSF13B
• Synonyms: TNFSF13B; TNF superfamily member 13b; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20; tumor necrosis factor ligand superfamily member 13B; ApoL related ligand TALL-1; B-cell-activating factor; B-lymphocyte stimulator; Delta4 BAFF; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; delta BAFF; dendritic cell-derived TNF-like molecule; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4
• Gene ID: 10673
• mRNA Refseq: NM_001145645.2
• Protein Refseq: NP_001139117.1
• UniProt ID: Q9Y275