Recombinant Human TNFSF11, FLAG-tagged
Cat.No. : | TNFSF11-473H |
Product Overview : | Human RANKL (aa 152-317) is fused at the N-terminus to a FLAG-tag. |
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Species : | Human |
Source : | HEK293 |
Tag : | Flag |
Protein Length : | 152-317 a.a. |
Description : | RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T cell proliferation. Important regulator of interactions between T cells and dendritic cells and may play a role in the regulation of the T cell-dependent immune response. RANKL plays an important role in the progression of breast cancer. |
Form : | Lyophilized. Contains PBS. |
Molecular Mass : | ~28kDa (SDS-PAGE) |
Purity : | ≥95% (SDS-PAGE) |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
Concentration : | 0.1mg/ml after reconstitution. |
Gene Name | TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 [ Homo sapiens ] |
Official Symbol | TNFSF11 |
Synonyms | TNFSF11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11; CD254; ODF; OPGL; RANKL; TRANCE; osteoprotegerin ligand; osteoclast differentiation factor; TNF-related activation-induced cytokine; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; sOdf; OPTB2; hRANKL2; |
Gene ID | 8600 |
mRNA Refseq | NM_003701 |
Protein Refseq | NP_003692 |
MIM | 602642 |
UniProt ID | O14788 |
Chromosome Location | 13q14 |
Pathway | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL6-mediated signaling events, organism-specific biosystem; Osteoblast Signaling, organism-specific biosystem; Osteoclast Signaling, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; |
Function | cytokine activity; cytokine activity; receptor activity; tumor necrosis factor receptor binding; tumor necrosis factor receptor superfamily binding; |
◆ Recombinant Proteins | ||
TNFSF11-2650H | Recombinant Human TNFSF11 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
TNFSF11-4154H | Recombinant Human Tumor Necrosis Factor (ligand) Superfamily, Member 11, GST-tagged | +Inquiry |
Tnfsf11-247M | Active Recombinant Mouse Tnfsf11, Fc-tagged | +Inquiry |
TNFSF11-P1002H | Recombinant Human Osteoprotegerin Ligand | +Inquiry |
TNFSF11-5859R | Recombinant Rat TNFSF11 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
TNFSF11-1586MCL | Recombinant Mouse TNFSF11 cell lysate | +Inquiry |
TNFSF11-998HCL | Recombinant Human TNFSF11 cell lysate | +Inquiry |
TNFSF11-1093HCL | Recombinant Human TNFSF11 cell lysate | +Inquiry |
TNFSF11-001CCL | Recombinant Cynomolgus TNFSF11 cell lysate | +Inquiry |
Not For Human Consumption!
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