Recombinant Human TNFRSF17 Protein, Fc\Avi-tagged

• Cat.No.: TNFRSF17-191H
• Product Overview: Biotinylated Recombinant Human B-cell Maturation Protein is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a Fc, Avi tag at the C-terminus.

Specification

• Species: Human
• Source: Human Cells
• Tag: Avi&Fc
• Description: B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• AA Sequence: Met1-Ala54
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Shipping: Ambient

Gene Information

• Gene Name: TNFRSF17 TNF receptor superfamily member 17 [ Homo sapiens (human) ]
• Official Symbol: TNFRSF17
• Synonyms: Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; BCM; BCMA; CD269; TNFRSF13A
• Gene ID: 608
• mRNA Refseq: NM_001192.3
• Protein Refseq: NP_001183.2
• MIM: 109545
• UniProt ID: Q02223