Recombinant Human Thioredoxin-Like 1, His-tagged

• Cat.No.: TXNL1-3421H
• Product Overview: Recombinant human TXNL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: TXNL1, also known as TRP32, TXL or TXL-1, is a cytoplasmic protein that participates in endocytotic signaling pathways and acts as a redox sensor. Expressed throughout the body, TXNL1 functions to couple oxidative stress to endocytosis, thereby regulating the GDI. Additionally, overexpression of TXNL1 inhibits cell proliferation by predisposing the cell to G0/G1 arrest, suggesting that TXNL1 also functions as a transcriptional repressor.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol.
• Molecular Weight: 34.4 kDa (309aa) confirmed by MALDI-TOF.
• Purity: > 95% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MVGVKPVGSD PDFQPELSGA GSRLAVVKFT MR G CGPCLRI APAFSSMSNK YPQAVFLEVD VHQCQGTAAT NNISATPTFL FF RNK VRIDQ YQGADAVGLE EKIKQHLEND PGSNEDTDIP KGYMDLMPFI NKA GC EC LNE SDEHGFDNCL RKDTTFLESD CDEQLLITVA FNQPVKLYSM KFQGPDNGQG PK YVKIFINL PRSMDFEEAE RSEPTQALEL TEDDIKEDGI VPLRYVKFQN VNS VTI F VQS NQGEEETTRI SYFTFIGTPV QATNMNDFKR VVGKKGESH.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: TXNL1 thioredoxin-like 1 [ Homo sapiens ]
• Synonyms: thioredoxin-like 1; Txl; TXNL; TRP32; TXL-1; TXNL1; thioredoxin-like protein 1; thioredoxin-related protein 1; 32 kDa thioredoxin-related protein; thioredoxin -related 32 kDa protein; thioredoxin-like, 32kDa; TXL
• Gene ID: 9352
• mRNA Refseq: NM_004786
• Protein Refseq: NP_004777
• MIM: 603049
• UniProt ID: O43396
• Chromosome Location: 18q21.31
• Function: disulfide oxidoreductase activity; electron carrier activity; protein disulfide oxidoreductase activity