Recombinant Human THAP1, His-tagged

• Cat.No.: THAP1-15857H
• Product Overview: Recombinant human THAP1protein, fused to His tag at N-terminus, was expressed in E.coli.

Specification

• Description: THAP domain-containing protein 1, also known as THAP1, is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAPtype zinc finger, a conserved DNA-binding domain. It is a DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. THAP1 may also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 10% glycerol, 1mM DTT, 0.2M NaCl
• Molecular Mass: 27.5 kDa (237aa)
• Protein length: 1-213 aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMVQSCS AYGCKNRYDK DKPVSFHKFP LTRPSLCKEW EAAVRRKNFK PTKYSSICSE HFTPDCFKRE CNNKLLKENA VPTIFLCTEP HDKKEDLLEP QEQLPPPPLP PPVSQVDAAI GLLMPPLQTP VNLSVFCDHN YTVEDTMHQR KRIHQLEQQVEKLRKKLKTA QQRCRRQERQ LEKLKEVVHF QKEKDDVSER GYVILPNDYF EIVEVPA
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: THAP1 THAP domain containing, apoptosis associated protein 1 [ Homo sapiens ]
• Official Symbol: THAP1
• Synonyms: THAP1; THAP domain containing, apoptosis associated protein 1; dystonia 6, torsion (autosomal dominant) , DYT6; 4833431A01Rik; FLJ10477
• Gene ID: 55145
• mRNA Refseq: NM_018105
• Protein Refseq: NP_060575
• MIM: 609520
• UniProt ID: Q9NVV9
• Chromosome Location: 8p11.1