Recombinant Human TGFB1

Cat.No. : TGFB1-196H
Product Overview : Recombinant human TGFB1 (279-end) was expressed in E.coli cells and purified by proprietary chromatographic techniques.
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Species : Human
Source : E.coli
Tag : Non
Protein Length : 279-end a.a.
Description : TGFB1 or transforming growth factor, beta 1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. High levels of TGFB1 protein have been localized in developing cartilage, endochondral and membrane bone, and skin and play a key role in the growth and differentiation of these tissues. TGFB1 can upregulate gene expression of its own converting enzyme furin in tumor cells, and mutations in TGFB1 gene result in Camurati-Engelmann disease.
Form : Recombinant protein stored in 1 X PBS, 10% glycerol.
Molecular Mass : ~14 kDa
Endotoxin : Less than 0.1 ng/μg (IEU/μg) of TNF-alpha.
Purity : >95% by densitometry
Applications : Cell Assay
Storage : Stored at desiccated below -20oC. It is stable at 4oC between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and mu
Concentration : 0.2 μg/μl
Gene Name TGFB1 transforming growth factor, beta 1 [ Homo sapiens ]
Official Symbol TGFB1
Synonyms TGFB1; transforming growth factor, beta 1; DPD1, TGFB; transforming growth factor beta-1; Camurati Engelmann disease; CED; TGFbeta; TGF-beta-1; TGF-beta 1 protein; latency-associated peptide; LAP; DPD1; TGFB;
Gene ID 7040
mRNA Refseq NM_000660
Protein Refseq NP_000651
MIM 190180
UniProt ID P01137
Chromosome Location 19q13.1
Pathway ACE Inhibitor Pathway, organism-specific biosystem; ALK1 signaling events, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem;
Function enzyme binding; eukaryotic cell surface binding; growth factor activity; protein N-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding;

Not For Human Consumption!

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