Recombinant Human TESK1, GST-tagged

• Cat.No.: TESK1-7024H
• Product Overview: Recombinant full-length human TESK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: Full length
• Description: TESK1 or testis-specific kinase 1 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain which is most closely related to those of the LIM motif-containing protein kinases (LIMKs). TESK1 protein can phosphorylate myelin basic protein and histone in vitro and plays an important role at and after the meiotic phase of spermatogenesis. TESK1 is mainly expressed in testicular germ cells.
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~106 kDa
• Purity: >70%
• Applications: Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1 μg/μl

Gene Information

• Gene Name: TESK1 testis-specific kinase 1 [ Homo sapiens ]
• Official Symbol: TESK1
• Synonyms: TESK1; testis-specific kinase 1; dual specificity testis-specific protein kinase 1; testis specific kinase 1; testicular protein kinase 1
• Gene ID: 7016
• mRNA Refseq: NM_006285
• Protein Refseq: NP_006276
• MIM: 601782
• UniProt ID: Q15569
• Chromosome Location: 9p13
• Pathway: Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-extracellular matrix interactions, organism-specific biosystem; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components, organism-specific biosystem
• Function: ATP binding; metal ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity